Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. 2024
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Nature. 2024 Mar;627(8003):407-415. PMID: 38383779 doi: 10.1038/s41586-024-07079-8.
Arndts K, Kegele J, Ritter M, Prazeres da Costa C, Hoerauf A, Winkler AS. 2024
Active infection with Onchocerca volvulus and the linkage to epilepsy/nodding syndrome.
PLoS Negl Trop Dis. 2024 May 9;18(5):e0012076. doi: 10.1371/journal.pntd.0012076. eCollection 2024 May. PMID: 38722927
Brinkmann BJ, Floerchinger A, Schniederjohann C, Roider T, Coelho M, Mack N, Bruch PM, Liebers N, Dötsch S, Busch DH, Schmitt M, Neumann F, Roessner PM, Seiffert M, Dietrich S. 2024
CD20-bispecific antibodies improve response to CD19-CAR T-cells in lymphoma in-vitro and CLL in-vivo models.
Blood. 2024 May 28:blood.2023022682. PMID: 38805637 doi: 10.1182/blood.2023022682.
Cai C, Keoshkerian E, Wing K, Samir J, Effenberger M, Schober K, Bull RA, Lloyd AR, Busch DH, Luciani F. 2024
Discovery of a monoclonal, high-affinity CD8+ T-cell clone following natural hepatitis C virus infection.
Immunol Cell Biol. 2024 Aug;102(7):630-641. doi: 10.1111/imcb.12791. Epub 2024 Jun 10. PMID: 38855806
Carr A, Mateyka LM, Scheu SJC , Bici A, Paijmans J, Reijmers RM, Dieminger N, Dildebekova S, Hamed N, Wagner K, Busch DH and D'Ippolito E. 2024
Advances in preclinical TCR characterization: leveraging cell avidity to identify functional TCRs
Biol Chem 2024 Apr 29. PMID: 38666334 DOI: 10.1515/hsz-2023-0341
Castillo JG, DeBarge R, Mende A, Tenvooren I, Marquez DM, Straub A, Busch DH, Spitzer MH, DuPage M. 2024
A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis.
bioRxiv [Preprint]. 2024 Jan 12:2024.01.11.575237. PMID: 38260336 doi: 10.1101/2024.01.11.575237.
Cook-Deegan M, Böge K, Bruchhausen W, Chagunda M, Chaturvedi M, Esen M, Hanefeld J, Kampmann B, Köhler C, Köhler C, Osei F, Prazeres da Costa C, Rehfuess E, Velavan TP, Anton N. 2024
Beyond buzzwords: fostering interdisciplinary and collaborative global health research in Germany and beyond.
Glob Health Action. 2024 Dec 31;17(1):2408884. doi: 10.1080/16549716.2024.2408884. Epub 2024 Oct 21. PMID: 39428984
Drost F, Dorigatti E, Straub A, Hilgendorf P, Wagner KI, Heyer K, López Montes M, Bischl B, Busch DH, Schober K, Schubert B. 2024
Predicting T cell receptor functionality against mutant epitopes.
Cell Genom 2024 Aug 8:100634. PMID: 39151427 doi: 10.1016/j.xgen.2024.100634.
Engelsberger V, Gerhard M, Mejías-Luque R. 2024
Effects of Helicobacter pylori infection on intestinal microbiota, immunity and colorectal cancer risk.
Front Cell Infect Microbiol. 2024 Jan 26;14:1339750. doi: 10.3389/fcimb.2024.1339750. eCollection 2024. PMID: 38343887
Esser E, Schulte EC, Graf A, Karollus A, Smith NH, Michler T, Dvoretskii S, Angelov A, Sonnabend M, Peter S, Engesser C, Radonic A, Thürmer A, von Kleist M, Gebhardt F, da Costa CP, Busch DH, Muenchhoff M, Blum H, Keppler OT, Gagneur J, Protzer U. 2024
Viral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events.
Sci Rep. 2024 Mar 8;14(1):5768. doi: 10.1038/s41598-024-56162-7. PMID: 38459123
Fan XH, Zhang Y, Wang P, Song QQ, Wang M, Mejias-Luque R, Li ZX, Zhou T, Zhang JY, Liu WD, Zhang LF, Li WQ, You WC, Gerhard M, Jiao YC, Wang XB, Pan KF. 2024
A noninvasive multianalytical approach establishment for risk assessment and gastric cancer screening.
Int J Cancer. 2024 Mar 15;154(6):1111-1123. doi: 10.1002/ijc.34739. Epub 2023 Oct 16. PMID: 37842828
Fuchs S, Gong R, Gerhard M, Mejías-Luque R.
Immune Biology and Persistence of Helicobacter pylori in Gastric Diseases.
Curr Top Microbiol Immunol. 2023;444:83-115. doi: 10.1007/978-3-031-47331-9_4. PMID: 38231216
Hesari DK, Aljadeeah S, Brhlikova P, Hyzam D, Komakech H, Rueda JSP, Cañas JO, Ching C, Orubu S, Acevedo OB, Basaleem H, Orach CG, Zaman M, Prazeres da Costa. 2024
Access to and utilisation of antimicrobials among forcibly displaced persons in Uganda, Yemen and Colombia: a pilot cross-sectional survey.
C BMJ Open 2024 Jul 16;14(7):e084734 PMID: 39013652 DOI: 10.1136/bmjopen-2024-084734
Khan F, Müller TR, Kasmapour B, Ynga-Durand MA, Eiz-Vesper B, von Einem J, Busch DH, Cicin-Sain L. 2024
Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen.
Front Immunol. 2024 Jul 15;15:1439184. doi: 10.3389/fimmu.2024.1439184. eCollection 2024. PMID: 39104541
Kocher K, Moosmann C, Drost F, Schülein C, Irrgang P, Steininger P, Zhong J, Träger J, Spriewald B, Bock C, Busch DH, Bogdan C, Schubert B, Winkler TH, Tenbusch M, Schuster EM, Schober K. 2024
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual.
Lancet Infect Dis. 2024 May;24(5):e272-e274. doi: 10.1016/S1473-3099(24)00134-8. Epub 2024 Mar 4. PMID: 38452777
Lacher SB., Dörr J, de Almeida GP, Hönninger J, Bayerl F, Hirschberger A, Pedde AM, Meiser P, Ramsauer L, Rudolph TJ, Spranger N, Morotti M, Grimm AJ, Jarosch S, Oner A, Gregor L, Lesch S, Michaelides S, Fertig L, Briukhovetska D, Majed L, Stock S, Busch DH, Buchholz VR, Knolle PA, Zehn D, Dangaj Laniti D, Kobold S, Böttcher JP. 2024
PGE2 limits effector expansion of tumor-infiltrating stem-like CD8+ T cells.
Nature. 2024 May; 629(8011):417-425. doi: 10.1038/s41586-024-07254-x. Epub 2024 Apr 24. PMID: 38658748
Lema YL, Prodjinotho UF, Makasi C, Nanyaro MA, Kilale AM, Mfinanga S, Stelzle D, Schmidt V, Carabin H, Winkler AS, Lyamuya EF, Ngowi BJ, Chachage M, Prazeres da Costa C. 2024
Evaluating the modulation of peripheral immune profile in people living with HIV and (Neuro)cysticercosis.
PLoS Negl Trop Dis. 2024 Aug 2;18(8):e0012345 PMID: 39093864 DOI: 10.1371/journal.pntd.0012345
Li ZX, Bronny K, Formichella L, Mejías-Luque R, Burrell T, Macke L, Lang U, Vasapolli R, Hysenaj O, Stallforth I, Vieth M, You WC, Zhang Y, Suerbaum S, Schulz C, Pan KF, Gerhard M. 2024
A multiserological line assay to potentially discriminate current from past Helicobacter pylori infection.
Clin Microbiol Infect. 2024 Jan;30(1):114-121. doi: 10.1016/j.cmi.2023.10.006. Epub 2023 Oct 11. PMID: 37827383
Makasi CE, Ngowi B, Mahande MJ, Welte TM, Stelzle D, Guga G, Schmidt V, Rüther C, Lema Y, Prodjinotho UF, Kilale A, Prazeres da Costa C, Mmbaga BT , Winkler AS. 2024
Neurocysticercosis and cognitive impairment among people with epilepsy in Taenia solium endemic regions of rural southern Tanzania: A hospital-based cross-sectional study in mental health clinics of selected sites in Tanzania.
Epilepsy Behav. 2024 Oct; 159:110010 PMID: 39186856 DOI: 10.1016/j.yebeh.2024.110010
Manske K, Dreßler L, Fräßle SP, Effenberger M, Tschulik C, Cletiu V, Benke E, Wagner M, Schober K, Müller TR, Stemberger C, Germeroth L, Busch DH, Poltorak MP. 2024
Miniaturized CAR knocked onto CD3ε extends TCR function with CAR specificity under control of endogenous TCR signaling cascade.
J Immunol Methods. 2024 Mar;526:113617. doi: 10.1016/j.jim.2024.113617. Epub 2024 Jan 11. PMID: 38215900
Pan KF, Li WQ , Zhang L, Liu WD, Ma JL, Zhang Y, Ulm K, Wang JX, Zhang L, Bajbouj M, Zhang LF, Li M, Vieth M, Quante M, Wang LH, Suchanek S, Mejías-Luque R, Xu HM, Fan XH, Han X, Liu ZC, Zhou T, Guan WX, Schmid RM, Gerhard M, Classen M, You WC. 2024
Gastric cancer prevention by community eradication of Helicobacter pylori: a cluster-randomized controlled trial.
Nat Med. 2024 Jul 30. Online ahead of print. PMID: 39079993 doi: 10.1038/s41591-024-03153-w
Rothe K, Bachfischer T, Karapetyan S, Hapfelmeier A, Wurst M, Gleich S, Dichtl K, Schmid RM, Triebelhorn J, Wagner L, Erber J, Voit F, Burgkart R, Obermeier A, Seybold U, Busch DH, Rämer PC, Spinner CD, Schneider J. 2024
Are enterococcal bloodstream infections an independent risk factor for a poorer 5-year survival or just a marker for severity of illness?The Munich multicentric enterococci cohort.
Microbiol Spectr. 2023 Dec 12;11(6):e0258523. doi: 10.1128/spectrum.02585-23. Epub 2023 Oct 4. PMID: 37791770
Saggau C, Bacher P, Esser D, Rasa M, Meise S, Mohr N, Kohlstedt N, Hutloff A, Schacht SS, Dargvainiene J, Martini GR, Stürner KH, Schröder I, Markewitz R, Hartl J, Hastermann M, Duchow A, Schindler P, Becker M, Bautista C, Gottfreund J, Walter J, Polansky JK, Yang M, Naghavian R, Wendorff M, Schuster EM, Dahl A, Petzold A, Reinhardt S, Franke A, Wieczorek M, Henschel L, Berger D, Heine G, Holtsche M, Häußler V, Peters C, Schmidt E, Fillatreau S, Busch DH, Wandinger KP, Schober K, Martin R, Paul F, Leypoldt F, Scheffold A. 2024
Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases.
Immunity. 2024 Oct 8;57(10):2416-2432.e8. doi: 10.1016/j.immuni.2024.08.005. Epub 2024 Sep 2. PMID: 39226901
Sauerborn E, Carolina Corredor N, Reska T, Perlas A, da Fonseca Atum SV, Goldman N, Wantia N, Prazeres da Costa C, Foster-Nyarko E, Urban L. 2024
Detection of hidden antibiotic resistance through real-time genomics.
Nat Commun. 2024 June 28;15(1):5494 PMID: 38944650 DOI: 10.1038/s41467-024-49851-4
Sèyigbéna P DGB, Honkpèhedji YJ, Ludwig E, Mahmoudou S, Prodjinotho FU, Adamou R, P Nouatin O, R Adégbitè B, Dejon-Agobe JC, Mba RB, Maloum M, Nkoma AM, Zinsou JF, Luty AJ, Esen M, Ayôla AA, Prazeres da Costa C. 2024
Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes.
Sci Rep. 2024 June 27; 14(1):14845 PMID: 38937587 DOI: 10.1038/s41598-024-65232-9
Svec M, Dötsch S, Warmuth L, Trebo M, Fräßle S, Riddell SR, Jäger U, D'Ippolito E, Busch DH. 2024
A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells.
Front Immunol. 2024 Jan 11;14:1268698. doi: 10.3389/fimmu.2023.1268698. eCollection 2023. PMID: 38274808
Ursch LT, Müschen JS, Ritter J, Klermund J, Bernard BE, Kolb S, Warmuth L, Andrieux G, Miller G, Jiménez-Muñoz M, Theis FJ, Boerries M, Busch DH, Cathomen T, Schumann K. 2024
Modulation of TCR stimulation and pifithrin-α improve the genomic safety profile of CRISPR-engineered human T cells
Cell Rep Med. 2024 Dec 17;5(12):101846. doi: 10.1016/j.xcrm.2024.101846. Epub 2024 Dec 4. PMID: 39637860
Winterhalter PM, Warmuth L, Hilgendorf P, Schuetz JM, Dötsch S, Tonn T, Cicin-Sain L MD PhD, Busch DH, Schober K. 2024
HLA reduction of human T cells facilitates generation of immunologically multi-compatible cellular products.
Blood Adv. 2024 Apr 19:bloodadvances.2023011496. doi: 10.1182/bloodadvances.2023011496. Online ahead of print. PMID: 38640254