Current publications
Publications of the year 2024

Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. 2024

B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.

Nature. 2024 Mar;627(8003):407-415. PMID: 38383779 doi: 10.1038/s41586-024-07079-8

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Brinkmann BJ, Floerchinger A, Schniederjohann C, Roider T, Coelho M, Mack N, Bruch PM, Liebers N, Dötsch S, Busch DH, Schmitt M, Neumann F, Roessner PM, Seiffert M, Dietrich S. 2024

CD20-bispecific antibodies improve response to CD19-CAR T-cells in lymphoma in-vitro and CLL in-vivo models.

Blood. 2024 May 28:blood.2023022682. PMID: 38805637 doi: 10.1182/blood.2023022682

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Carr A, Mateyka LM, Scheu SJC , Bici A, Paijmans J, Reijmers RM, Dieminger N, Dildebekova S, Hamed N, Wagner K, Busch DH and D'Ippolito E. 2024

Advances in preclinical TCR characterization: leveraging cell avidity to identify functional TCRs

Biol Chem 2024 Apr 29. PMID: 38666334 DOI: 10.1515/hsz-2023-0341

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Castillo JG, DeBarge R, Mende A, Tenvooren I, Marquez DM, Straub A, Busch DH, Spitzer MH, DuPage M. 2024

A mass cytometry approach to track the evolution of T cell responses during infection and immunotherapy by paired T cell receptor repertoire and T cell differentiation state analysis.

bioRxiv [Preprint]. 2024 Jan 12:2024.01.11.575237. PMID: 38260336 doi: 10.1101/2024.01.11.575237

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Drost F, Dorigatti E, Straub A, Hilgendorf P, Wagner KI, Heyer K, López Montes M, Bischl B, Busch DH, Schober K, Schubert B. 2024

Predicting T cell receptor functionality against mutant epitopes.

Cell Genom 2024 Aug 8:100634. PMID: 39151427 doi: 10.1016/j.xgen.2024.100634.

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Esser E, Schulte EC, Graf A, Karollus A, Smith NH, Michler T, Dvoretskii S, Angelov A, Sonnabend M, Peter S, Engesser C, Radonic A, Thürmer A, von Kleist M, Gebhardt F, da Costa CP, Busch DH, Muenchhoff M, Blum H, Keppler OT, Gagneur J, Protzer U. 2024

Viral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events.

Sci Rep. 2024 Mar 8;14(1):5768. doi: 10.1038/s41598-024-56162-7. PMID: 38459123

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Hesari DK, Aljadeeah S, Brhlikova P, Hyzam D, Komakech H, Rueda JSP, Cañas JO, Ching C, Orubu S, Acevedo OB, Basaleem H, Orach CG, Zaman M, Prazeres da Costa. 2024

Access to and utilisation of antimicrobials among forcibly displaced persons in Uganda, Yemen and Colombia: a pilot cross-sectional survey. 

C BMJ Open 2024 Jul 16;14(7):e084734 PMID: 39013652 DOI: 10.1136/bmjopen-2024-084734 

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Hildenbrand K, Bohnacker S, Rajeev Menon P, Kerle A, Prodjinotho UF, Hartung F, Strasser PC, Catici DAM, Rührnößl F, Haslbeck M, Schumann K, Müller SI, Prazeres da Costa C, Esser-von Bieren J, Matthias J Feige J. 2023

Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions.

Sci Adv. 2023 Oct 27;9(43):eadg6874. PMID: 37878703 PMCID: PMC10599630 doi: 10.1126/sciadv.adg6874. Epub 2023 Oct 25.

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Kocher K, Moosmann C, Drost F, Schülein C, Irrgang P, Steininger P, Zhong J, Träger J, Spriewald B, Bock C, Busch DH, Bogdan C, Schubert B, Winkler TH, Tenbusch M, Schuster EM, Schober K. 2024

Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual.

Lancet Infect Dis. 2024 May;24(5):e272-e274. doi: 10.1016/S1473-3099(24)00134-8. Epub 2024 Mar 4. PMID: 38452777

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Lacher SB., Dörr J, de Almeida GP, Hönninger J, Bayerl F, Hirschberger A, Pedde AM, Meiser P, Ramsauer L, Rudolph TJ, Spranger N, Morotti M, Grimm AJ, Jarosch S, Oner A, Gregor L, Lesch S, Michaelides S, Fertig L, Briukhovetska D, Majed L, Stock S, Busch DH, Buchholz VR, Knolle PA, Zehn D, Dangaj Laniti D, Kobold S, Böttcher JP. 2024

PGE2 limits effector expansion of tumor-infiltrating stem-like CD8+ T cells.

Nature. 2024 May; 629(8011):417-425. doi: 10.1038/s41586-024-07254-x. Epub 2024 Apr 24. PMID: 38658748

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Lema YL, Prodjinotho UF, Makasi C, Nanyaro MA, Kilale AM, Mfinanga S, Stelzle D, Schmidt V, Carabin H, Winkler AS, Lyamuya EF, Ngowi BJ, Chachage M, Prazeres da Costa C. 2024

Evaluating the modulation of peripheral immune profile in people living with HIV and (Neuro)cysticercosis.   

PLoS Negl Trop Dis. 2024 Aug 2;18(8):e0012345 PMID: 39093864 DOI: 10.1371/journal.pntd.0012345 

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Li ZX, Bronny K, Formichella L, Mejías-Luque R, Burrell T, Macke L, Lang U, Vasapolli R, Hysenaj O, Stallforth I, Vieth M, You WC, Zhang Y, Suerbaum S, Schulz C, Pan KF, Gerhard M. 2024

A multiserological line assay to potentially discriminate current from past Helicobacter pylori infection.

Clin Microbiol Infect. 2024 Jan;30(1):114-121. doi: 10.1016/j.cmi.2023.10.006. Epub 2023 Oct 11. PMID: 37827383

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Makasi CE, Ngowi B,  Mahande MJ,  Welte TM, Stelzle D, Guga G, Schmidt V,  Rüther C, Lema Y, Prodjinotho UF, Kilale A, Prazeres da Costa C,  Mmbaga BT ,  Winkler AS. 2024

Neurocysticercosis and cognitive impairment among people with epilepsy in Taenia solium endemic regions of rural southern Tanzania: A hospital-based cross-sectional study in mental health clinics of selected sites in Tanzania. 

Epilepsy Behav. 2024 Oct; 159:110010 PMID: 39186856 DOI: 10.1016/j.yebeh.2024.110010 

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Manske K, Dreßler L, Fräßle SP, Effenberger M, Tschulik C, Cletiu V, Benke E, Wagner M, Schober K, Müller TR, Stemberger C, Germeroth L, Busch DH, Poltorak MP. 2024

Miniaturized CAR knocked onto CD3ε extends TCR function with CAR specificity under control of endogenous TCR signaling cascade.

J Immunol Methods. 2024 Mar;526:113617. doi: 10.1016/j.jim.2024.113617. Epub 2024 Jan 11. PMID: 38215900

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Pan KF, Li WQ , Zhang L, Liu WD, Ma JL, Zhang Y, Ulm K, Wang JX, Zhang L, Bajbouj M, Zhang LF, Li M, Vieth M, Quante M, Wang LH, Suchanek S, Mejías-Luque R, Xu HM, Fan XH, Han X, Liu ZC, Zhou T, Guan WX, Schmid RM, Gerhard M, Classen M, You WC. 2024

Gastric cancer prevention by community eradication of Helicobacter pylori: a cluster-randomized controlled trial.

Nat Med. 2024 Jul 30. Online ahead of print. PMID: 39079993 doi: 10.1038/s41591-024-03153-w

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Rothe K, Bachfischer T, Karapetyan S, Hapfelmeier A, Wurst M, Gleich S, Dichtl K, Schmid RM, Triebelhorn J, Wagner L, Erber J, Voit F, Burgkart R, Obermeier A, Seybold U, Busch DH, Rämer PC, Spinner CD, Schneider J. 2024

Are enterococcal bloodstream infections an independent risk factor for a poorer 5-year survival or just a marker for severity of illness?The Munich multicentric enterococci cohort.

Microbiol Spectr. 2023 Dec 12;11(6):e0258523. doi: 10.1128/spectrum.02585-23. Epub 2023 Oct 4. PMID: 37791770

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Sauerborn E,  Carolina Corredor N,  Reska T, Perlas A, da Fonseca Atum SV, Goldman N, Wantia N, Prazeres da Costa C, Foster-Nyarko E, Urban L. 2024

Detection of hidden antibiotic resistance through real-time genomics. 

Nat Commun. 2024 June 28;15(1):5494 PMID: 38944650 DOI: 10.1038/s41467-024-49851-4 

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Sèyigbéna P DGB, Honkpèhedji YJ, Ludwig E, Mahmoudou S, Prodjinotho FU, Adamou R, P Nouatin O, R Adégbitè B, Dejon-Agobe JC, Mba RB, Maloum M, Nkoma AM, Zinsou JF,  Luty AJ, Esen M, Ayôla AA, Prazeres da Costa C. 2024

Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes. 

Sci Rep. 2024 June 27; 14(1):14845 PMID: 38937587 DOI: 10.1038/s41598-024-65232-9

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Svec M, Dötsch S, Warmuth L, Trebo M, Fräßle S, Riddell SR, Jäger U, D'Ippolito E, Busch DH. 2024

A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells.

Front Immunol. 2024 Jan 11;14:1268698. doi: 10.3389/fimmu.2023.1268698. eCollection 2023. PMID: 38274808

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Winterhalter PM, Warmuth L, Hilgendorf P, Schuetz JM, Dötsch S, Tonn T, Cicin-Sain L MD PhD, Busch DH, Schober K. 2024

HLA reduction of human T cells facilitates generation of immunologically multi-compatible cellular products.

Blood Adv. 2024 Apr 19:bloodadvances.2023011496. doi: 10.1182/bloodadvances.2023011496. Online ahead of print. PMID: 38640254

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