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Proteomic Diversity in Bacteria: Insights and Implications for Bacterial Identification.
Mol Cell Proteomics. 2025 Mar;24(3):100917. doi: 10.1016/j.mcpro.2025.100917. Epub 2025 Jan 27. PMID: 39880082
Albrecht C, Sanchin A, Joerger AK, Delbridge C, Boeckh-Behrens T, Wantia N, Wunderlich S, Wessels L, Vajkoczy P, Meyer B, Wostrack M. 2025
Mycotic aneurysms as a rare cause of subarachnoid hemorrhage.
Sci Rep. 2025 Sep 23;15(1):32683. doi: 10.1038/s41598-025-20673-8. PMID: 40987818 Free PMC article.
Ben Khaled N, Schulz C, Alunni-Fabbroni M, Bronny K, Jochheim LS, Kalali B, Öcal O, Seidensticker M, Piseddu I, Enssle S, Karin M, Schneider JS, Strasoldo-Graffemberg T, Koch N, Macke L, Reiter FP, Lange CM, Wang Y, De Toni EN, Gerhard M, Mayerle J, Ricke J, Malfertheiner P. 2025
Impact of Helicobacter pylori on Immune Checkpoint Inhibition in Hepatocellular Carcinoma: A Multicenter Study.
Digestion. 2025 Feb 19:1-11. doi: 10.1159/000542847. Online ahead of print. PMID: 39970893
Bülbül A, Hönninger J, Buchholz VR. 2025
Who is who in differentiation of Trm-like TIL.
Immunity. 2025 Jul 8;58(7):1620-1622. doi: 10.1016/j.immuni.2025.06.013. PMID: 40633526
Chen W, Qiu M, Paizs P, Sadowski M, Ramonaite T, Zborovsky L, Mejias-Luque R, Janßen KP, Kinross J, Goldin RD, Rebec M, Liebeke M, Takats Z, McKenzie JS, Strittmatter N. 2025
Universal, untargeted detection of bacteria in tissues using metabolomics workflows.
Nat Commun. 2025 Jan 2;16(1):165. doi: 10.1038/s41467-024-55457-7. PMID: 39747039
Fischer JC, Göttert S, Giller M, Heinrich P, Fan K, Khalid O, Walther CN, Drießlein M, Nefzger SM, Eisenkolb G, Timnik VR, Jarosch S, Klostermeier L, Engleitner T, Strieder N, Gebhard C, Diederich S, Schmid NA, Lansink Rotgerink L, Joachim L, Ghimire S, Vonbrunn E, Büttner-Herold M, Remke M, Steiger K, Öllinger R, Rad R, Wolff D, Feuerer M, Hoffmann P, Edinger M, Rehli M, Tschurtschenthaler M, Kepp O, Kroemer G, Thiele Orberg E, Combs SE, Herr W, Bassermann F, Busch DH, Holler E, Heidegger S, Poeck H. 2025
Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury.
Signal Transduct Target Ther. 2025 Nov 26;10(1):384. doi: 10.1038/s41392-025-02476-5. PMID: 41290566 Free PMC article.
Fritschle K, Mielke M, Seelbach OJ, Mühlthaler U, Živanić M, Bozoglu T, Dötsch S, Warmuth L, Busch DH, Skerra A, Kupatt C, Weber WA, Randall RE, Steiger K, Morath V. 2025
The V5-Epitope Tag for Cell Engineering and Its Use in Immunohistochemistry and Quantitative Flow Cytometry.
Biology (Basel). 2025 Jul 20;14(7):890. doi: 10.3390/biology14070890. PMID: 40723447
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Helicobacter pylori γ-glutamyltransferase is linked to proteomic adaptions important for colonization.
Gut Microbes. 2025 Dec;17(1):2488048. doi: 10.1080/19490976.2025.2488048. Epub 2025 Apr 9. PMID: 40205659
Füchsl F, Schwanzer A, Faber M, Rieger L, Zuleger G, Auf der Maur P, Cruz E, Braun S, Öllinger R, Busch DH, Bassermann F, Krackhardt AM. 2025
Tempered signal strength via low-dose MEK inhibition optimizes therapeutic performance of engineered T cells.
J Immunother Cancer. 2025 Dec 1;13(12):e012800. doi: 10.1136/jitc-2025-012800. PMID: 41330614 Free PMC article.
Gong R, Huang B, Ralser A, Friedrich V, Mibus C, Engelsberger V, Koch MRA, Skerhut M, Giese T, Andrä I, Vieth M, van Gisbergen KPJM, Semper RP, Gerhard M, Mejías-Luque R. 2025
CagA-dependent Hobit+ gastric tissue-resident memory T cells confer full protection from Helicobacter pylori reinfection.
Gut. 2025 Jun 5:gutjnl-2025-334781. doi: 10.1136/gutjnl-2025-334781. Online ahead of print. PMID: 40473399
Holle J, Reitmeir R, Behrens F, Singh D, Schindler D, Potapenko O, McParland V, Anandakumar H, Kanzelmeyer N, Sommerer C, Hartleif S, Andrassy J, Heemann U, Neuenhahn M, Forslund-Startceva SK, Gerhard M, Oh J, Wilck N, Löber U, Bartolomaeus H. 2025
Gut microbiome alterations precede graft rejection in kidney transplantation patients.
Am J Transplant. 2025 Feb 18:S1600-6135(25)00093-0. doi: 10.1016/j.ajt.2025.02.010. Online ahead of print. PMID: 39978595
Jobin K, Seetharama D, Rüttger L, Fenton C, Kharybina E, Wirsching A, Huang A, Knöpper K, Kaisho T, Busch DH, Vaeth M, Saliba AE, Graw F, Pulfer A, González SF, Zehn D, Liang Y, Ugur M, Gasteiger G, Kastenmüller W. 2025
A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals.
Science. 2025 Apr 11;388(6743):eadq1405. doi: 10.1126/science.adq1405. Epub 2025 Apr 11. PMID: 40208984
Kaeuferle T, Eiz-Vesper B, Moosmann A, Behrends U, Decker M, Gutjahr L, Mautner J, Klein F, Kreer C, Reger M, Busch DH, D'Ippolito E, Kohlmayer F, Menzel A, Willier S, Maecker-Kolhoff B, Feuchtinger T. 2025
Guiding Antiviral Cell Therapy Approaches with an Online Resource of Clinically Scored Epitopes, T-Cell Receptors, and B-Cell Receptors.
Transfus Med Hemother. 2025 Sep 18;52(6):350-359. doi: 10.1159/000548312. eCollection 2025 Dec. PMID: 41368235 Free PMC article.
Kocher K, Drost F, Tesfaye AM, Moosmann C, Schülein C, Grotz M, D'Ippolito E, Graw F, Spriewald B, Busch DH, Bogdan C, Tenbusch M, Schubert B, Schober K. 2025
Vaccination-induced T cell responses maintain polyclonality with high antigen receptor avidity.
Sci Immunol. 2025 Oct 3;10(112):eadu6730. doi: 10.1126/sciimmunol.adu6730. Epub 2025 Oct 3. PMID: 41042909
Kövilein J, Sorbie A, Khaloian S, Küntzel V, von Stern M, Ahmed M, Jarosch S, Remke M, Metwaly A, Reuss EM, Busch DH, Allez M, Steiger K, Schraml B, Coleman OI, Haller D. J. 2025
Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer.
Crohns Colitis. 2025 Jul 3;19(7):jjaf102. doi: 10.1093/ecco-jcc/jjaf102. PMID: 40662399
Lema YL, Prodjinotho UF, Makasi C, Nanyaro MA, Kilale AM, Godfrey Mfinanga S, Schmidt V, Carabin H, Winkler AS, Lyamuya EF, Ngowi BJ, Prazeres da Costa C. 2025
Cytokine profiles and CD4 counts in HIV-positive individuals with cysticercosis: implications for sex-specific immune responses in co-endemic regions of Tanzania.
Front Immunol. 2025 Feb 19;16:1521295. doi: 10.3389/fimmu.2025.1521295. eCollection 2025. PMID: 40046043
Li X, Tao HQ, Zhao JE, Zhu J, Du LB, Gerhard M, Li WQ. 2025
Helicobacter pylori infection, anti-Helicobacter pylori treatment and risk of colorectal cancer and adenoma: an observational study and a meta-analysis.
EClinicalMedicine. 2025 Jun 9;84:103299. doi: 10.1016/j.eclinm.2025.103299. eCollection 2025 Jun. PMID: 40547441
Mejias-Luque R, Gerhard M. 2025
Decoding the interplay: Helicobacter pylori infection, tumor immune microenvironment, and immunotherapy outcomes in gastrointestinal cancers.
Innovation (Camb). 2025 Mar 14;6(5):100880. doi: 10.1016/j.xinn.2025.100880. eCollection 2025 May 5. PMID: 40432785
Morath V, Fritschle K, Warmuth L, Anneser M, Dötsch S, Živanić M, Krumwiede L, Bösl P, Bozoglu T, Robu S, Libertini S, Kossatz S, Kupatt C, Schwaiger M, Steiger K, Busch DH, Skerra A, Weber WA. 2025
PET-based tracking of CAR T cells and viral gene transfer using a cell surface reporter that binds to lanthanide complexes.
Nat Biomed Eng. 2025 Jun 13. doi: 10.1038/s41551-025-01415-7. Online ahead of print. PMID: 40514433
Mucavele J, Nhancupe N, Monteiro GER, Miambo RD, Gouveia L, Pondja A, Sousa IM, Bickler SW, Benson CA, Schooley RT, Schmidt V, Ruether C, Stelzle D, Prazeres da Costa C, Suade L, Wainberg ML, Oquendo MA, Winkler AS, Noormahomed EV; Zambézia cysticercosis working Group. 2025
Cysticercosis and neurocysticercosis in people from Mocuba district, Zambézia province: A Mozambican community-based study.
PLoS Negl Trop Dis. 2025 May 13;19(5):e0013083. doi: 10.1371/journal.pntd.0013083. eCollection 2025 May. PMID: 40359426
Mujal AM, Owyong M, Santosa EK, Sauter JC, Grassmann S, Pedde AM, Meiser P, Wingert CK, Pujol M, Buchholz VR, Lau CM, Böttcher JP, Sun JC. 2025
Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells.
Immunity. 2025 Mar 11;58(3):585-600.e6. doi: 10.1016/j.immuni.2025.02.012. Epub 2025 Feb 28. PMID: 40023159
Petri K, D'Ippolito E, Künkele A, Köhl U, Busch DH, Einsele H, Hudecek M. 2025
Next-generation T cell immunotherapies engineered with CRISPR base and prime editing: challenges and opportunities.
Nat Rev Clin Oncol. 2025 Dec;22(12):902-923. doi: 10.1038/s41571-025-01072-4. Epub 2025 Sep 19. PMID: 40973826 Review.
Sabersky-Müssigbrodt H, Russell S, Wantia N, Hayden O. 2025
Rapid direct disk diffusion testing for antibiotic resistance in urinary tract infections: a bacterial concentration-adjusted approach.
Microbiol Spectr. 2025 Nov 4;13(11):e0088825. doi: 10.1128/spectrum.00888-25. Epub 2025 Sep 22. PMID: 40981441
Sasidharan Nair V, Yu Z, Ahmadi H, Bonifacius A, Pietzsch B, Busch DH, Cicin-Sain L, Müller F, Schober K, Eiz-Vesper B, Floess S, Huehn J. 2025
Epigenetically Controlled ZEB2 Expression Promotes the Cytotoxic Potential of CMV-Specific CD8+ T Cells.
Eur J Immunol. 2025 Nov;55(11):e70084. doi: 10.1002/eji.70084. PMID: 41195865 Free PMC article.
Schulz C, Liou JM, Alboraie M, Bornschein J, Campos Nunez C, Coelho LG, Quach DT, Fallone CA, Chen YC, Gerhard M, Gisbert JP, Jung HY, Katelaris PH, Kim JG, Lu H, Macke L, Mahachai V, Moss SF, Remes Troche JM, Riquelme A, Romano M, Setshedi M, Smith S, Suerbaum S, Tshibangu-Kabamba E, Vilaichone RK, Yadegar A, Yamaoka Y, Mégraud F, El-Omar EM, Sugano K, Malfertheiner P. 2025
Helicobacter pylori antibiotic resistance: a global challenge in search of solutions.
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Endoscopic healing in pediatric IBD perpetuates a persistent signature defined by Th17 cells with molecular and microbial drivers of disease.
Cell Rep Med. 2025 Jul 15;6(7):102236. doi: 10.1016/j.xcrm.2025.102236. PMID: 40669446
Sternkopf LE, Prodjinotho UF, Gres V, Repgen N, Steiger K, Schluckebier J, Sikasunge CS, Stelzle D, Makasi C, Winkler AS, Ngowi BJ, Villalobos N, Ebner F, Häcker G, Henneke P, Prazeres da Costa C. 2025
Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction.
Front Immunol. 2025 Sep 25;16:1603385. doi: 10.3389/fimmu.2025.1603385. eCollection 2025. PMID: 41080538
Straub A, Abedi Z, Busch DH, Buchholz VR. 2025
Nurture over nature in fate decisions of antigen-specific CD8+ T cell clones from an endogenous repertoire.
Immunity. 2025 Oct 14;58(10):2355-2356. doi: 10.1016/j.immuni.2025.09.005. PMID: 41092890 No abstract available.
Sukums F, Ngowi B, Chaula R, Weiszhar KL, Kalinga A, Ivanova O, Prazeres da Costa C, Hoerauf A, Sahay S, Noormahomed EV, Debrah LB, Sikasunge C, Ngowi H, Winkler AS. 2025
Experiences of Health Research Data Sharing Among Researchers in Sub-Saharan Africa: Cross-Sectional Study.
JMIR Form Res. 2025 Oct 23;9:e69411. doi: 10.2196/69411. PMID: 41129781 Free PMC article.
Wagner L, Schneider H, Luppa PB, Schröder K, Wantia N, Querbach C, Jeske SD, Lahmer T, Rothe K, Dibos M, Voit F, Erber J, Spinner CD, Schneider J, Triebelhorn J. 2025
Evaluation of a host-protein signature score for differentiating between bacterial and viral infections: real-life evidence from a German tertiary hospital.
Infection. 2025 Jun;53(3):883-891. doi: 10.1007/s15010-024-02384-w. Epub 2024 Sep 9. PMID: 39249176
Wagner L, Wurst M, Erber J, Bachfischer T, Haller B, Gleich S, Dichtl K, Schmid RM, Triebelhorn J, Voit F, Seybold U, Busch DH, Rämer PC, Spinner CD, Schneider J, Rothe K. 2025
Risk factors for vancomycin resistance in patients with Enterococcus faecium bloodstream infections: an analysis of the Munich Multicentric Enterococci Cohort.
Microbiol Spectr. 2025 Jul;13(7):e0005225. doi: 10.1128/spectrum.00052-25. Epub 2025 Jun 5. PMID: 40470938