Publications of the year 2023

Aguilar R., Li X., Crowell C.S., Burrell T., Vidal M., Rubio R., Jiménez A., Hernández-Luis P., Hofmann D., Mijočević H., Jeske S., Christa C, D'Ippolito E., Lingor P., Knolle P.A., Roggendorf H., Priller A., Yazici S., Carolis C., Mayor A., Schreiner P., Poppert H., Beyer H., Schambeck S.E., Izquierdo L., Tortajada M., Angulo A., Soutschek E., Engel P., Garcia-Basteiro A., Busch D.H., Moncunill G., Protzer U., Dobaño C., Gerhard M. 2023

RBD-Based ELISA and Luminex Predict Anti-SARS-CoV-2 Surrogate-Neutralizing Activity in Two Longitudinal Cohorts of German and Spanish Health Care Workers

Microbiology Spectrum, 2023 Jan 9. PMID: 36622140 DOI: 10.1128/spectrum.03165-22

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Arndts K, Kegele J, Massarani AS, Ritter M, Wagner T, Pfarr K, Lämmer C, Dörmann P, Peisker H, Menche D, Al-Bahra M, Prazeres da Costa C, Schmutzhard E, Matuja W, Hoerauf A, Layland-Heni LE, Winkler AS. 2023

Epilepsy and nodding syndrome in association with an Onchocerca volvulus infection drive distinct immune profile patterns.

PLoS Negl Trop Dis. 2023 Aug 3;17(8):e0011503 PMID: 37535695. DOI: 10.1371/journal.pntd.0011503

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Dötsch S, Svec M, Schober K, Hammel M, Wanisch A , Gökmen F, Jarosch S, Warmuth L, Barton J, Cicin-Sain L, D'Ippolito E, Dirk H Busch D.H. 2023

Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression

Proc Natl Acad Sci U S A. 2023 Mar 7;120(10): e2200626120.PMID: 36853939 PMCID: PMC10013756 DOI: 10.1073/pnas.2200626120

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Fraessle S.P., Tschulik C., Effenberger M., Cletiu V., Gerget M., Schober K., Busch D.H., Germeroth L., Stemberger C., Poltorak M.P.

Activation-inducible CAR expression enables precise control over engineered CAR T cell function.

Commun Biol. 2023 Jun 5;6(1):604. PMID: 37277433 PMCID: PMC10241805 DOI: 10.1038/s42003-023-04978-w Free PMC article.

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Friedrich V, Gerhard M. 2023

Vaccination against Helicobacter pylori - An approach for cancer prevention?

Mol Aspects Med. 2023 Aug;92:101183. DOI: 10.1016/j.mam.2023.101183. Epub 2023 Apr 3. PMID: 37018869 Review.

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Grzegorek K, Kroidl I, Prazeres da Costa C, Rothe C. 2023

Spectrum of helminth infections in migrants from Sub-Saharan Africa to Europe: a literature review.

Am J Trop Med Hyg. 2023 Apr 24;108(6):1096-1104 PMID: 37094791. DOI: 10.4269/ajtmh.22-0354

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Horkova V., Drobek A., Paprckova D., Niederlova V, Prasai A., Uleri V., Glatzova D., Kraller M., Cesnekova M., Janusova S., Salyova E., Tsyklauri O., Kadlecek T.A. Krizova K., Platzer R., Schober K., Busch D.H., Weiss A., Huppa J.B., Stepanek O. 2023

Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells

Nat Immunol. 2023 Jan;24(1):174-185. PMID: 36564464 PMCID: PMC9810533 DOI: 10.1038/s41590-022-01366-0

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Jarosch S., Köhlen J., Ghimire S., Thiele Orberg E., Hammel M., Gaag D., Evert M., Janssen K.P., Hiergeist A., Gessner A., Weber D., Meedt E., Poeck H., D'Ippolito E., Holler E., Busch D.H. 2023

Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD

Cell Rep Med. 2023 Jul 18;4(7): 101125.PMID: 37467715 PMCID: PMC10394271 DOI: 10.1016/j.xcrm.2023.101125

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Koch M.R.A., Gong R., Friedrich V., Engelsberger V., Kretschmer L., Wanisch A., Jarosch S., Ralser A., Lugen B., Quante M., Vieth M., Vasapolli R., Schulz C., Buchholz V.R., Busch D.H., Mejías-Luque R., Gerhard M. 2023

CagA-specific gastric CD8+ tissue-resident T cells control Helicobacter pylori during the early infection phase.

Gastroenterology (2023); PMID: 36587707 DOI: https://doi.org/10.1053/j.gastro.2022.12.016

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Kretschmer L., Fuchs N., Busch D.H., Buchholz V.R. 2023

Picking up speed: cell cycle regulation during effector CD8+ T cell differentiation

Med Microbiol Immunol. 2023 Jun;212(3):253-260. PMID: 37277539 PMCID: PMC10293348 DOI:10.1007/s00430-023-00772-xexternal) . Epub 2023 Jun 6.

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Nguyen QA, Schmitt L, Mejías-Luque R, Gerhard M. 2023

Effects of Helicobacter pylori adhesin HopQ binding to CEACAM receptors in the human stomach.

Front Immunol. 2023 Feb 20;14:1113478. DOI: 10.3389/fimmu.2023.1113478. eCollection 2023. PMID: 36891299

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Pachmayr L.O., Muehlbauer A, Flommersfeld S, Graml F, Hoenninger J, von Baumgarten L, Buchholz V.R, Grassmann S. 2023

Unbiased chemokine receptor screening reveals similar efficacy of lymph node- and tumor-targeted T cell immunotherapy.

Cancer immunology, immunotherapy : CII, 10.1007/s00262-023-03472-w. PMID: 37301772 PMCID: PMC10412482 DOI: 10.1007/s00262-023-03472-w

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Peng L, Guo Y, Gerhard M, Gao JJ, Liu ZC, Mejías-Luque R, Zhang L, Vieth M, Ma JL, Liu WD, Li ZX, Zhou T, Li WQ, You WC, Zhang Y, Pan KF. 2023

Metabolite Alterations and Interactions with Microbiota in Helicobacter pylori-Associated Gastric Lesions.

Microbiol Spectr. 2023 Aug 17;11(4):e0534722. DOI: 10.1128/spectrum.05347-22 . Epub 2023 Jun 26. PMID: 37358459

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Ralser A, Dietl A, Jarosch S, Engelsberger V, Wanisch A, Janssen KP, Middelhoff M, Vieth M, Quante M, Haller D, Busch DH, Deng L, Mejías-Luque R, Gerhard M. 2023

Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature.

Gut. 2023 Jul;72(7):1258-1270. DOI: 10.1136/gutjnl-2022-328075. Epub 2023 Apr 4. PMID: 37015754

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Rothe K, Bachfischer T, Karapetyan S, Hapfelmeier A, Wurst M, Gleich S, Dichtl K, Schmid RM, Triebelhorn J, Wagner L, Erber J, Voit F, Burgkart R, Obermeier A, Seybold U, Busch DH, Rämer PC, Spinner CD, Schneider J.

Are enterococcal bloodstream infections an independent risk factor for a poorer 5-year survival or just a marker for severity of illness?The Munich multicentric enterococci cohort.

Microbiol Spectr. 2023 Dec 12;11(6):e0258523. doi: 10.1128/spectrum.02585-23(link is external). Epub 2023 Oct 4. PMID: 37791770

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Schick J, Altunay M, Lacorcia M, Schubart C, Bodendorfer B, Christensen D, Alexander C, Wirtz S, Vöhringer D, Prazeres da Costa C, Lang R. 2023

IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity.

Elife. 2023 Feb 8;12:e72923. PMID: 36753434. DOI: 10.7554/eLife.72923

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Schulz C, Kalali B, Link A, Gerhard M, Malfertheiner P. 2023

New Rapid Helicobacter Pylori Blood Test Based on Dual Detection of FliD and CagA Antibodies for On-Site Testing.

Clin Gastroenterol Hepatol. 2023 Jan;21(1):229-231.e1. DOI: 10.1016/j.cgh.2021.11.008 . Epub 2021 Nov 16. PMID: 34793965

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Seigner J, Zajc CU, Dötsch S, Eigner C, Laurent E, Busch DH, Lehner M, Traxlmayr MW.

Solving the mystery of the FMC63-CD19 affinity.

Sci Rep. 2023 Dec 27;13(1):23024. doi: 10.1038/s41598-023-48528-0. PMID: 38155191

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Stelzle D, Makasi C, Schmidt V, Trevisan C, Van Damme I, Ruether C, Dorny P, Magnussen P, Zulu G, Mwape KE , Bottieau E, Prazeres da Costa C, Prodjinotho UF, Carabin H, Jackson E, Fleury A, Gabriël S, Ngowi BJ, Winkler AS. 2023

Efficacy and safety of antiparasitic therapy for neurocysticercosis in rural Tanzania: a prospective cohort study.

Infection Aug;51(4):1127-1139 2023 PMID: 36961623. DOI: 10.1007/s15010-023-02021-y

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Straub A., Grassmann S., Jarosch S., Richter L., Hilgendorf P., Hammel M., Wagner K.I., Buchholz V.R., Schober K., Busch D.H. 2023

Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection.

Immunity. 2023 May 5;S1074-7613(23)00179-6 PMID: 37164014. DOI: 10.1016/j.immuni.2023.04.010

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Xu T., Philipp Karschnia P., Loureiro Cadilha B., Dede S., Lorenz M., Seewaldt N., Nikolaishvili E., Müller K., Blobner J., Nico Teske N., Herold J.J., Kai Rejeski K., Langer S., Obeck H., Lorenzini T., Mulazzani M., Zhang W., Ishikawa-Ankerhold H., Buchholz V.R., Subklewe M., Thon N., Straube A., Tonn J.C., Kobold S., von Baumgarten L. 2023

In vivo dynamics and anti-tumor effects of EpCAM-directed CAR T-cells against brain metastases from lung cancer

Oncoimmunology. 2023 Jan 13;12(1):2163781. PMID: 36687005 PMCID: PMC9851202 DOI: 10.1080/2162402X.2022.2163781

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