The **Sino-German Summer Workshop** aims to provide an international forum for the exchange of scientific knowledge and advancements related to the microbiota in the upper gastrointestinal (GI) tract. This workshop brings together leading researchers, clinicians, and experts to discuss microbiome interactions, their role in disease mechanisms, and translational applications for cancer treatment and prevention.

Recent studies highlight the profound influence of the microbiome on immune responses and cancer progression, particularly in gastric carcinoma, gastroesophageal junction tumors, and esophageal adenocarcinoma. Discussions will focus on the latest advancements in microbiota sequencing, bacterial mechanisms in disease, biobank studies, and novel immunotherapeutic strategies. The workshop also aims to facilitate collaboration between European and Asian researchers, fostering future multicentric studies and clinical trials.

Topics covered will include the role of Helicobacter pylori in gastric cancer, the potential therapeutic applications of microbiota, and the integration of multi-omics data for translational research. With the increasing need for precision medicine, this workshop will serve as a platform for networking and knowledge exchange to advance microbiota-based therapeutic approaches.

Friday, July 25th 2025

08:30 - Welcome

Session I. Helicobacter pylori

• 08:40 - Helicobacter pylori immune responses and their impact on vaccine development - Markus Gerhard
• 09:05 - Helicobacter pylori - Alexander Link
• 09:30 - Helicobacter pylori-induced up-regulation of CEACAM expression: a double-edged sword  - Raquel Mejías-Luque
• 09:55 - Helicobacter pylori Metabolomics - Christian Schulz

10:20 - Coffee Break

• 10:45 - Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection - Li Deng
• 11:10 - Helicobacter pylori and Microbiota in Gastric Cancer Development - Yang Zhang
• 11:35 - Gastric Cancer Prevention by Eradication of Helicobacter pylori - Kai-Feng Pan
• 12:00 - Helicobacter pylori  Eradication Trials - Hei Sunny Wong

12:25 Lunch Break

Session II. Non-Helicobacter microbiota, GI pathology and immunotherapy

• 14:00 - Non-Helicobacter Microbiota stomach microbiome in the pathogenesis of gastric cancer - Jun Yu, Xiang Jennifer Zhang
• 14:25 - Eco-evolutionary mechanisms of microbiota-mediated infection protection - Bärbel Stecher
• 14:50 - Gastric Cancer Screening in the EU - is it feasible? - Stepan Suchanek

15:15 - Coffee Break

• 15:35 - Nuclear Receptors and Metabolites - Elke Burgermeister
• 16:00 - Microbiota and immunotherapy of GI cancers - Matthias Ebert
• 16:25 - BLoss of bile acid-dependent inhibition of FXR accelerates carcinogenesis of gastroesophageal adenocarcinoma - Michael Quante
• 16:50 - First histological signs of Invasion in Gastric carcinoma - Michael Vieth

17:15 - Final Discussion and Concluding Remarks

Markus Gerhard, Technical University Munich, Munich, Germany

Alexander Link, Otto-von-Guerike-universität Magdeburg, Magdeburg, Germany

Raquel Mejías-Luque, Technical University Munich, Munich, Germany

Christian Schulz, Ludwig-Maximillians-Universität München, Munich, Germany

Li Deng, Technical University Munich, Munich, Germany

Yang Zhang, State Key Laboratory of Holistic Integrative Management of GI Cancers Peking University (PKU), Beijing, China

Kai-Feng Pan, State Key Laboratory of Holistic Integrative Management of GI Cancers Peking University (PKU), Beijing, China

Hei Sunny Wong, Nanyang Technical University (NTU), Singapore

Jun Yu, State Key Lab of Digestive Disease Chinese University of Hongkong (CUHK)

Xiang Jennifer Zhang, State Key Lab of Digestive Disease Chinese University of Hongkong (CUHK)

Bärbel Stecher, Technical University Munich, Munich, Germany

Stepan Suchanek, Military University Hospital Prague, Prague

Thomas Miethke, University of Heidelberg, Heidelberg, Germany

Elke Burgermeister, University of Heidelberg, Heidelberg, Germany

Matthias Ebert, University of Heidelberg, Heidelberg, Germany

Michael Quante, University of Freiburg, Freiburg, Germany

Michael Vieth, FAU Erlangen-Nürnberg, Bayreuth, Germany

For registration to the meeting, please download the form below, save it and return per e-mail to: pylotum.mih@mh.tum.de. 

Do not forget to indicate whether you will attend the meeting in person or online.

Online attendees will receive a link after registration

The workshop will take place in Munich, the vibrant capital of Bavaria, a city that seamlessly blends rich history with modern allure. Known for its stunning architecture, from the ornate Nymphenburg Palace to the iconic towers of Frauenkirche, Munich charms visitors at every turn. It’s home to world-class museums, including the Deutsches Museum and Alte Pinakothek, and famous for its lush parks like the expansive Englischer Garten. With a thriving beer culture celebrated at Oktoberfest and cozy beer gardens, Munich offers a taste of Bavarian tradition. At time of the workshop, early July, the weather is usually warm, but not yet hot, and thus is the perfect season for visiting Munich and its beautiful surroundings. 

Venue

The workshop will take place at the 
TranslaTUM
Technische Universität München
Einsteinstrasse 25
81675 München

For inquiries, please contact:

Venue and Travel Organization:

• Katarina Djurasović - Tel. +49 89 4140 4122, katarina.djurasovic@tum.de

Organizing Committee:

• PD Dr. Raquel Mejías-Luque (raquel.mejias-luque@tum.de)
• PD Dr. Elke Burgermeister (elke.burgermeister@medma.uni-heidelberg.de)
• Prof. Markus Gerhard (markus.gerhard@tum.de)

© 2025 Sino-German Summer Workshop | Technical University of Munich