Hesari DK, Aljadeeah S, Brhlikova P, Hyzam D, Komakech H, Rueda JSP, Cañas JO, Ching C, Orubu S, Acevedo OB, Basaleem H, Orach CG, Zaman M, Prazeres da Costa. 2024
Access to and utilisation of antimicrobials among forcibly displaced persons in Uganda, Yemen and Colombia: a pilot cross-sectional survey.
C BMJ Open 2024 Jul 16;14(7):e084734 PMID: 39013652 DOI: 10.1136/bmjopen-2024-084734
***
Sauerborn E, Carolina Corredor N, Reska T, Perlas A, da Fonseca Atum SV, Goldman N, Wantia N, Prazeres da Costa C, Foster-Nyarko E, Urban L. 2024
Detection of hidden antibiotic resistance through real-time genomics.
Nat Commun. 2024 June 28;15(1):5494 PMID: 38944650 DOI: 10.1038/s41467-024-49851-4
***
Makasi CE, Ngowi B, Mahande MJ, Welte TM, Stelzle D, Guga G, Schmidt V, Rüther C, Lema Y, Prodjinotho UF, Kilale A, Prazeres da Costa C, Mmbaga BT , Winkler AS.
Neurocysticercosis and cognitive impairment among people with epilepsy in Taenia solium endemic regions of rural southern Tanzania: A hospital-based cross-sectional study in mental health clinics of selected sites in Tanzania.
Epilepsy Behav. 2024 Oct; 159:110010 PMID: 39186856 DOI: 10.1016/j.yebeh.2024.110010
***
Sèyigbéna P DGB, Honkpèhedji YJ, Ludwig E, Mahmoudou S, Prodjinotho FU, Adamou R, P Nouatin O, R Adégbitè B, Dejon-Agobe JC, Mba RB, Maloum M, Nkoma AM, Zinsou JF, Luty AJ, Esen M, Ayôla AA, Prazeres da Costa C.
Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes.
Sci Rep. 2024 June 27; 14(1):14845 PMID: 38937587 DOI: 10.1038/s41598-024-65232-9
***
Lema YL, Prodjinotho UF, Makasi C, Nanyaro MA, Kilale AM, Mfinanga S, Stelzle D, Schmidt V, Carabin H, Winkler AS, Lyamuya EF, Ngowi BJ, Chachage M, Prazeres da Costa C.
Evaluating the modulation of peripheral immune profile in people living with HIV and (Neuro)cysticercosis.
PLoS Negl Trop Dis. 2024 Aug 2;18(8):e0012345 PMID: 39093864 DOI: 10.1371/journal.pntd.0012345
***
Esser E, Schulte EC, Graf A, Karollus A, Smith NH, Michler T, Dvoretskii S, Angelov A, Sonnabend M, Peter S, Engesser C, Radonic A, Thürmer A, von Kleist M, Gebhardt F, da Costa CP, Busch DH, Muenchhoff M, Blum H, Keppler OT, Gagneur J, Protzer U. 2024
Viral genome sequencing to decipher in-hospital SARS-CoV-2 transmission events.
Sci Rep. 2024 Mar 8;14(1):5768. doi: 10.1038/s41598-024-56162-7. PMID: 38459123
***
Hildenbrand K, Bohnacker S, Rajeev Menon P, Kerle A, Prodjinotho UF, Hartung F, Strasser PC, Catici DAM, Rührnößl F, Haslbeck M, Schumann K, Müller SI, Prazeres da Costa C, Esser-von Bieren J, Feige MJ. 2023
Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions.
Sci Adv. 2023 Oct 27;9(43):eadg6874. PMID: 37878703 PMCID: PMC10599630 doi: 10.1126/sciadv.adg6874. Epub 2023 Oct 25
***.
Arndts K, Kegele J, Massarani AS, Ritter M, Wagner T, Pfarr K, Lämmer C, Dörmann P, Peisker H, Menche D, Al-Bahra M, Prazeres da Costa C, Schmutzhard E, Matuja W, Hoerauf A, Layland-Heni LE, Winkler AS.
Epilepsy and nodding syndrome in association with an Onchocerca volvulus infection drive distinct immune profile patterns.
PLoS Negl Trop Dis. 2023 Aug 3;17(8):e0011503 PMID: 37535695. DOI: 10.1371/journal.pntd.0011503
***
Stelzle D, Makasi C, Schmidt V, Trevisan C, Van Damme I, Ruether C, Dorny P, Magnussen P, Zulu G, Mwape KE , Bottieau E, Prazeres da Costa C, Prodjinotho UF, Carabin H, Jackson E, Fleury A, Gabriël S, Ngowi BJ, Winkler AS.
Efficacy and safety of antiparasitic therapy for neurocysticercosis in rural Tanzania: a prospective cohort study.
Infection Aug;51(4):1127-1139 2023 PMID: 36961623. DOI: 10.1007/s15010-023-02021-y
***
Schick J, Altunay M, Lacorcia M, Schubart C, Bodendorfer B, Christensen D, Alexander C, Wirtz S, Vöhringer D, Prazeres da Costa C, Lang R.
IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity.
Elife. 2023 Feb 8;12:e72923. PMID: 36753434. DOI: 10.7554/eLife.72923
***
Grzegorek K, Kroidl I, Prazeres da Costa C, Rothe C.
Spectrum of helminth infections in migrants from Sub-Saharan Africa to Europe: a literature review.
Am J Trop Med Hyg. 2023 Apr 24;108(6):1096-1104 PMID: 37094791. DOI: 10.4269/ajtmh.22-0354
***
Sitali MC, Schmidt V, Mwenda R, Sikasunge CS, Mwape KE, Simuunza MC, Prazeres da Costa C, Winkler AS, Phiri IK.
Experimental animal models and their use in understanding cysticercosis: A systematic review.
PLoS One. 2022 Jul 19;17(7):e0271232. eCollection 2022. PMID: 35853079. DOI: 10.1371/journal.pone.0271232
***
Langa I, Padama F, Nhancupe N, Pondja A, Hlashwayo D, Gouveia L, Stelzle D, Prazeres da Costa C, Schmidt V, Winkler AS, Noormahomed EV.
The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique.
2022 PLoS Negl Trop Dis 16(7): e0010606. PMID 35834558. DOI: 10.1371/journal.pntd.0010606
***
Hamway Y, Zimmermann K, Blommers MJJ, Sousa M, Häberli C, Kulkarni S, Skalicky S, Hackl M, Götte M, Keiser J, Prazeres da Costa C, Spangenberg T, Azzaoui K.
Modulation of Host-Parasite Interactions with Small Molecules Targeting Schistosoma mansoni microRNAs.
ACS Infect Dis. 2022 Sep 13. Epub ahead of print. PMID: 36098656. DOI: 10.1021/acsinfecdis.2c00360
***
Lacorcia M, Kugyelka R, Spechtenhauser L, Prodjinotho F, Hamway Y, Spangenberg T, Prazeres da Costa C.
Praziquantel Reduces Maternal Mortality and Offspring Morbidity by Enhancing Anti-Helminthic Immune Responses.
Front Immunol. 2022 Jun 27;13:878029. PMID: 35833137. DOI: 10.3389/fimmu.2022.878029
***
Prodjinotho UF, Gres V, Fiona Henkel F, Schmidt V, Winkler AS, Sikasunge C, Hennecke P, Esser-von Bieren J, Prazeres da Costa C.
Helminthic dehydrogenase drives PGE2 and IL‐10 production in monocytes to potentiate Treg induction.
EMBO Rep. 2022 May 4;23(5):e54096. PMID: 35357743. DOI: 10.15252/embr.202154096
***
Erber J, Kappler V, Haller B, Mijočević H, Galhoz A, Prazeres da Costa C, Gebhardt F, Graf N, Hoffmann D, Thaler M, Lorenz E, Roggendorf H, Kohlmayer F, Henkel A, Menden M P, Ruland J, Spinner C D, Protzer U, Knolle P, Lingor P.
Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany.
Emerg Infect Dis. 2022 Mar;28(3):572-581. PMID: 35195515. DOI: 10.3201/eid2803.204436
***
Zöllkau J, Ankert J, Pletz MW, Mishra S, Seliger G, Lobmaier SM, Prazeres da Costa C, Seidel V, Weizsäcker KV, Jablonka A, Dopfer C, Baier M, Horvatits T, Reiter-Owona I, Groten T, Schleenvoigt BT.
Hepatitis E, Schistosomiasis and Echinococcosis-Prevalence in a Cohort of Pregnant Migrants in Germany and Their Influence on Fetal Growth Restriction.
Pathogens. 2022 Jan 3;11(1):58. PMID: 35056006. DOI: 10.3390/pathogens11010058
***
Penkler M, Jacob CM, Müller R, Kenney M, Shane A Norris SA, Prazeres da Costa C, Richardson SS, Roseboom TJ, Hanson M.
Developmental Origins of Health and Disease, resilience and social justice in the COVID era.
J Dev Orig Health Dis. 2022 Aug;13(4):413-416. PMID: 34709151. DOI: 10.1017/S204017442100060X
***
Habib M, Esen M, Honkpehedji J, Klug SJ, Lobmaier S, Vogg K, Bustinduy AL, Ullrich A, Reinhard-Rupp J, Akim Adegnika A, Prazeres da Costa C.
The Challenges in Women’s Health in sub-Saharan Africa: Lessons learned from an integrative multistakeholder workshop in Gabon.
J Glob Health 2021 Sep 4;11:02002. doi: 10.7189/jogh.11.02002. eCollection 2021.
***
Habib M, Lange U, Ludwig S, Prazeres da Costa C.
The Impact of the COVID-19 Pandemic on Pregnancy, Birth and Sexual & Reproductive Health and Rights – Perspectives from Germany and Somalia.
J Glob Health 2021 Sep 4;11:03085. doi: 10.7189/jogh.11.03085. eCollection 2021.
***
Vejzagić N, Prodjinotho UF, El-Khafif N, Huang R, Simeonov A, Spangenberg T, Prazeres da Costa C.
Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.
PLoS Negl Trop Dis. 2021 May 25;15(5):e0009432. DOI: 10.1371/journal.pntd.0009432
***
Anisuzzaman, S. Frahm, U.F. Prodjinotho, S. Bhattacharjee, A. Verschoor, and C. Prazeres da Costa.
Host-Specific Serum Factors Control the Development and Survival of Schistosoma mansoni.
Front. Immunol., 2021, https://doi.org/10.3389/fimmu.2021.635622
***
Lacorcia M, Bhattacharjee S, Laubhahn K, Alhamdan F, Ram M, Muschaweckh A, Potaczek DP, Kosinska A, Garn H, Protzer U, Renz H, Prazeres da Costa C
Fetomaternal immune crosstalk modifies T cell priming through sustained changes to DC function.
J The Journal of allergy and clinical immunology, 2021 https://doi.org/10.1016/j.jaci.2021.02.031
***
de Lange A, Prodjinotho UF, Tomes H, Hagen J, Jacobs BA, Smith K, Horsnell W, Sikasunge C, Hockman D, Selkirk ME, Prazeres da Costa C, Raimondo JV.
Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling.
PLoS Negl Trop Dis. 2020 Dec21;14(12) PMID: 33347447 IF 3.88 DOI: 10.1371/journal.pntd.0008966
***
De los Reyes Jiménez M, Lechner A, Alessandrini F, Bohnacker S, Schindela S, Trompette A, Haimerl P, Thomas D, Henkel F, Mourão A, Geerlof A,Prazeres da Costa C, Chaker AM, Brüne B, Nüsing R, Jakobsson P, Nockher WA, Feige MJ, Haslbeck M, Ohnmacht C, Marsland BJ, Voehringer D, Harris NL, Schmidt-Weber CB, Esser-von
An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products.
J. Sci Transl Med 2020 Apr 22;12(540):eaay0605.DOI: 10.1126/scitranslmed.aay0605
***
Prodjinotho UF, Lema J, Lacorcia M, Schmidt V, Vejzagic N, Sikasunge C, Ngowi B, Winkler AS, Prazeres da Costa
Host immune responses during Taenia solium Neurocysticercosis infection and treatment.
CPLOS NTD April 16, 2020 https://doi.org/10.1371/journal.pntd.0008005
***
Ludwig E, Harder J, Lacorcia M, Honkpehedji JY, Nouatin O, van Dam GJ, Corstjens PLAM, Sartono E, Esen M, Lobmaier SM, Adegnika AA, Prazeres da Costa C
Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country.
Sci Rep. 2019 Oct 31;9(1):15776. DOI: 10.1038/s41598-019-52074-z
***
Eva Loffredo-Verde E, Bhattacharjee S, Malo A, Hasreiter J, Kosinska A, Ringelhan M, Heikenwaelder M, Protzer U*, Clarissa U. Prazeres da Costa C*
Dynamic, helminth-induced immune modulation influences the outcome of acute and chronic hepatitis B virus infection.
J Infect Dis.(link is external) 2019 Dec 25
***
Bhattacharjee S, Loffredo-Verde, Toska A, Flossdorf M, Mejías-Luque R, Gerhard M* and Prazeres da Costa C*.
Concomitant infection of S. mansoni and H. pylori promotes promiscuity of antigen experienced cells and primes the liver for a lower fibrotic response.
Cell Rep.(link is external) 2019 Jul 2;28(1):231-244.e5.
***
Klohe K, Amuasi J, Kaducu JM, Haavardsson I, Bogatyreva E, Onarheim KH, Harrison W, Kristensen F, Prazeres da Costa C* and Winkler AS*.
The 2017 Oslo conference report on neglected tropical diseases and emerging/re-emerging infectious diseases – focus on populations underserved.
Infectious Diseases of Poverty (2019) 8:40 DOI: 10.1186/s40249-019-0550-8
***
Frahm S, Anisuzzaman DVM, Prodjinotho F, Vejzagić N, Verschoor A and Prazeres da Costa C.
A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing.
PLOS NTD 2019 Jan 28;13(1): e0006590. doi: 10.1371 DOI: 10.1371/journal.pntd.0006590
***
Clifford K, Desai D, Prazeres da Costa C, Meyer H, Klohe K, Winkler AS, Rahman T, Islam T, Zaman MH.
Antimicrobial resistance in livestock and poor quality veterinary medicines.
Bull World Health Organ. 2018 Sep 1;96(9):662-664. DOI: 10.2471/BLT.18.209585
***
Dewals BG, Layland LE, Prazeres da Costa C, Horsnell WG
Maternal helminth infections and the shaping of offspring immunity.
Parasite Immunol. 2018 Oct 29:e12599.DOI: 10.1111/pim.12599
***
Lacorcia M and Prazeres da Costa C;
Maternal Schistosomiasis: Immunomodulatory Effects with Lasting Impact on Allergy and Vaccine Responses.
Front. Immunol. DOI: 10.3389/fimmu.2018.02960
***
Maeda H, Hatta T, Tsubokawa D, Mikami F, Nishimaki T, Nakamura T, Anisuzzaman, Matsubayashi M, Ogawa M, da Costa CP, Tsuji N.
Positive phototropism is accelerated in Biomphalaria glabrata snails by infection with Schistosoma mansoni.
Parasitol Int. 2018 Jun 9;67(5):609-611. DOI: 10.1016/j.parint.2018.06.003
***
Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B.
Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.
PLoS Biol. 2018 Apr 18;16(4):e2005504. DOI: 10.1371/journal.pbio.2005504
***
Winkler AS, Klohe K, Schmidt V, Haavardsson I, Abraham A, Prodjinotho UF, Ngowi B, Sikasunge C, Noormahomed E, Amuasi J, Kaducu J, Ngowi H, Abele-Ridder B, Harrison WE, Prazeres da Costa C.
Neglected tropical diseases - the present and the future.
Tidsskr Nor Laegeforen. 2018 Jan 2;138(3) DOI: 10.4045/tidsskr.17.0678
***
Rudelius M, Brehm K, Poelcher M, Spinner C, Rosenwald A, da Costa CP.
First case of human peritoneal cysticercosis mimicking peritoneal carcinosis: necessity of laparoscopy and histologic assessment for the correct diagnosis.
JMM Case Rep. 2017 Jun 8;4(6) DOI: 10.1099/jmmcr.0.005097(link is external)
Klohe K, Prazeres da Costa C, Lien N, Holmboe-Ottesen G, Rychlik M, Haavardsson I, Stordalen G, Singh S, Engebretsen I, Iversen PO, Winkler AS.
Nutrition – A global challenge for health.
Tidsskr Nor Laegeforen. 2017 Dec 12;137(23-24). DOI: 10.4045/tidsskr.17.0679
***
Klar K, Perchermeier S, Bhattacharjee S, Harb H, Adler T, Istvanffy R, Loffredo-Verde E, Oostendorp R, Renz H, Prazeres da Costa C.
Chronic schistosomiasis during pregnancy epigenetically reprograms T cell differentiation in offspring of infected mothers.
Eur J Immunol March 2017 DOI: 10.1002/eji.201646836
***
Roth S, Bergmann H, Jaeger M, Yeroslaviz A, Neumann K, Koenig PA, Prazeres da Costa C, Vanes L, Kumar V, Johnson M, Menacho-Márquez M, Habermann B, Tybulewicz VL, Netea M, Bustelo XR, Ruland J.
Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity.
Cell Rep. 2016 Dec 6 DOI: 10.1016/j.celrep.2016.11.018
***
Bhattacharjee S, Kalbfuss N, Prazeres da Costa C.
Parasites, microbiota and metabolic disease.
Parasite Immunol. 2016 Oct 7. DOI: 10.1111/pim.12390
***
Smits HH, Hiemstra PS, Prazeres da Costa C, Ege M, Edwards M, Garn H, Howarth PH, Jartti T, de Jong EC, Maizels RM, Marsland BJ, McSorley HJ, Müller A, Pfefferle PI, Savelkoul H, Schwarze J, Unger WW, von Mutius E, Yazdanbakhsh M, Taube C.
Microbes and asthma: Opportunities for intervention.
J Allergy Clin Immunol. 2016 Mar;137(3):690-7. DOI: 10.1016/j.jaci.2016.01.004
***
Kurz C, Schmidt V, Poppert H, Wilkins P, Noh J, Poppert S, Schlegel J, Delbridge C, da Costa CP, Winkler AS.
An Unusual Presentation of Neurocysticercosis: A Space-Occupying Lesion in the Fourth Ventricle Associated with Progressive Cognitive Decline.
Am J Trop Med Hyg. 2016 Jan;94(1):172-5. DOI: 10.4269/ajtmh.15-0099 . Epub 2015 Nov 30.
***
Loffredo-Verde E, Abdel-Aziz I, Layland L, Busch DH, Prazeres da Costa C.
Schistosome infection aggravates HCV-related liver disease and induces changes in the regulatory T cell phenotype.
Parasite Immunol. 2015 Jan 5. DOI: 10.1111/pim.12171
***
Straubinger K, Prazeres da Costa C.
Maternal helminth infections.
Adv Exp Med Biol. Oct 2014;828:27-48 DOI: 10.1007/978-1-4939-1489-0_2
***
Semper, R.P., Mejias-Luque, R., Gross, C., Anderl, F., Muller, A., Vieth, M., Busch, D.H., Prazeres da Costa, C., Ruland, J., Gross, O., and Gerhard, M.
Helicobacter pylori-Induced IL-1beta Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island.
J Immunol 2014. doi: 10.4049/jimmunol.1400362. DOI: 10.4049/jimmunol.1400362
***
Schwartz C, Oeser K, Prazeres da Costa C, Layland LE, Voehringer D.
T Cell-Derived IL-4/IL-13 Protects Mice against Fatal Schistosoma mansoni Infection Independently of Basophils
J Immunol. 2014 Oct 1;193(7):3590-9. DOI: 10.4049/jimmunol.1401155
***
Ritter M, Straubinger K, Schmidt S, Busch D, Hagner S, Garn H, Layland L, Prazeres da Costa
Functional relevance of NLRP3 inflammasome-mediated IL-1bduring acute allergic airway inflammation.
CClin Exp Immunol. 2014 Nov;178(2):212-23 DOI: 10.1111/cei.12400
***
Maternal Helminth Infection Determines Offspring Susceptibility to Allergic Airway Inflammation.
Straubinger K, Paul S, Prazeres da Costa O, Buch T, Busch DH, Layland L and Prazeres da Costa C.
J Allergy Clin Immunol. 2014Jul 18. pii: S0091-6749(14)00794-5
***
Holzscheiter M, Layland LE, Loffredo-Verde E, Mair K, Vogelmann R, Langer R, Wagner H, Prazeres da Costa C.
Lack of Host Gut Microbiota Alters Immune Responses and Intestinal Granuloma Formation during Schistosomiasis.
Clin Exp Immunol. 2013 Oct 30. DOI: 10.1111/cei.12230
***
Layland LE, Straubinger K, Ritter M, Loffredo-Verde E, Garn H, Sparwasser T, Prazeres da Costa C.
Schistosoma mansoni-mediated Suppression of Allergic Airway Inflammation Requires Patency and Foxp3+ Treg Cells.
PLOS NTD 2013 Aug 15;7(8):e2379. DOI: 10.1371/journal.pntd.0002379
***
Santner-Nanan B, Straubinger K, Hsu P, Parnell G, Tang B, Xu B, Makris A, Hennessy A, Peek M, Busch DH, Prazeres da Costa, Cand Nanan RJ
Fetal-maternal alignment of regulatory T cells correlates with Interleukin 10 and Bcl-2 upregulation in pregnancy.
Immunol. 2013 Jul 1;191(1):145-153. DOI: 10.4049/jimmunol.1203165
***
Desel C, Werninghaus K, Ritter M, Jozefowski K, Wenzel J, Russkamp N, Schleicher U, Christensen D, Wirtz S, Kirschning C, Agger E,da Costa CP and Lang R.
The Mincle-activating Adjuvant TDB Induces MyD88-dependent Th1 and Th17 Responses through IL-1R signaling.
PLoS One.2013;8(1): e53531. DOI: 10.1371/journal.pone.0053531
***
Tappe D, Berger L, Haeupler A, Muntau B, Racz P, Harder Y, Specht K, Prazeresda Costa C, Poppert S.
Molecular diagnosis of subcutaneous Spirometra erinaceieuropaeisparganosis in a Japanese immigrant.
Am J Trop Med Hyg. 2013 Jan;88(1):198-202. DOI: 10.4269/ajtmh.2012.12-0406
***
Nell M, Burgkart RH, Gradl G, von Eisenhart-Rothe R, Schaeffeler C, Trappe D,Prazeres da Costa C, Gradinger R, Kirchhoff C.
Primary extrahepatic alveolar echinococcosis of the lumbar spine and the psoas muscle: A Case Report and Review of Literature.
Ann Clin Microbiol Antimicrob.2011 Apr 15;10(1):13. DOI: 10.1186/1476-0711-10-13
***
Abdel-Aziz I, Layland LE, Prazeres da Costa C.
An imported case of external ophthalmomyiasis caused by the sheep botfly (Oestrus ovis) – case report.
Sci Parasitologica. 2010 Dec 11;4: 207-211
***
Ritter M, Gross O, Kays S, Ruland J, Nimmerjahn F, Saijo S, Tschopp J, Layland LE, Prazeres da Costa C.
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses.
Proc Natl Acad Sci U S A. 2010 Nov 8. DOI: 10.1073/pnas.1010337107
***
Layland LE, Mages J, Loddenkemper C, Hoerauf A, Wagner H, Lang R, da Costa CP.
Pronounced phenotype in activated regulatory T cells during a chronic helminth infection.
J Immunol. 2010 Jan 15;184(2):713-24. Epub 2009 Dec 9. DOI: 10.4049/jimmunol.0901435
***
Layland LE, Rad R, Wagner H,da Costa CU
Regulatory T cells primed in the absence of TLR2 fail to control Immunopathology and TH responses in Schistosomiasis.
Eur J Immunol. 2007 Aug;37(8):2174-84. https://doi.org/10.1002/eji.200737063
***
Costa CU, von Einsiedel HG, Disko R, Berthele A.
Multicystic tumor in the fourth ventricle: consider neurocysticercosis.
J Neurol.2006 Aug;253(8):1092-3. DOI: 10.1007/s00415-006-0155-6
***
Rad R, Brenner L, Bauer S, Schwendy S, Layland L, da Costa CP, Reindl W, Dossumbekova A, Friedrich M, Saur D, Wagner H, Schmid RM, Prinz C
CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo
Gastroenterology.2006 Aug;131(2):525-37. DOI: 10.1053/j.gastro.2006.05.001
***
Layland L, Wagner H, Prazeres da Costa C
Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni infected MyD88-deficient mice.
Eur J Immunol.2005 Nov;35(11):3248-57. DOI: 10.1002/eji.200526273
***
Rodriguez N, Fend F, Jennen L, Schiemann M, Wantia N, Prazeres da Costa C, Dürr S, Heinzmann U, Wagner H, Miethke T.
Polymorphonuclear neutrophils improve replication of Chlamydia pneumoniae in vivo upon MyD88-dependent attraction.
J Immunol.2005 Apr 15;174(8):4836-44. DOI: 10.4049/jimmunol.174.8.4836
***
da Costa CP, Wantia N, Kirschning C, Busch D, Rodriguez N, Wagner H, Miethke T.
Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo.
Eur J Immunol. 2004 Oct;34(10):2874-84. DOI: 10.1002/eji.200425101
***
Prebeck S, Brade H, Kirschning CJ, da Costa CP, Dürr S, Wagner H, Miethke T.
The Gram-negative bacterium Chlamydia trachomatis L2 stimulates tumor necrosis factor secretion by innate immune cells independently of its endotoxin.
Microbes Infect. 2003 May;5(6):463-70. DOI: 10.1016/s1286-4579(03)00063-7
***
da Costa CP, Neumann FJ, Kastrati A, Stallforth I, Schmid M, Joghetai N, Prebeck S, Wagner H, Miethke T.
Role of IgG-seropositivity to Chlamydia pneumoniae in early thrombotic events after coronary stent placement.
Atherosclerosis. 2003 Jan;166(1):171-6.). DOI: 10.1016/s0021-9150(02)00326-x
***
Vabulas RM, Braedel S, Hilf N, Singh-Jasuja H, Herter S, Ahmad-Nejad P, Kirschning CJ, Da Costa C, Rammensee HG, Wagner H, Schild H.
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway.
J Biol Chem. 2002 Jun 7;277(23):20847-53. DOI: 10.1074/jbc.M200425200
***
Donath B, Fischer C, Page S, Prebeck S, Jilg N, Weber M, da Costa C, Neumeier D, Miethke T, Brand K.
Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure.
Atherosclerosis. 2002 Nov;165(1):79-88. DOI: 10.1016/s0021-9150(02)00198-3
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da Costa CP, Kirschning CJ, Busch D, Dürr S, Jennen L, Heinzmann U, Prebeck S, Wagner H, Miethke T.
Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae.
Eur J Immunol. 2002 Sep;32(9):2460-70. DOI: 10.1002/1521-4141(200209)32:9<2460::AID-IMMU2460>3.0.CO;2-M
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Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Hacker H, Wagner H.
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells.
J Biol Chem. 2001 Aug 17;276(33):31332-9. 2001 Jun 11. DOI: 10.1074/jbc.M103217200
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Prebeck S, Kirschning C, Dürr S,da Costa C, Donath B, Brand K, Redecke V, Wagner H, Miethke T.
Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells.
J Immunol. 2001 Sep 15;167(6):3316-23. DOI: 10.4049/jimmunol.167.6.3316
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Neumann F, Kastrati A, Miethke T, Pogatsa-Murray G, Mehilli J, Valina C, Jogethaei N,da Costa CP, Wagner H, Schomig A.
Treatment of Chlamydia pneumoniae infection with roxithromycin and effect on neointima proliferation after coronary stent placement (ISAR-3): a randomised, double-blind, placebo-controlled trial.
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